[A ten year clinical investigation of injectable contraceptives]. / Investigacion clinica sobre diez anos de anticonceppion inyectable mensual.

ABSTRACT

PIP The article describes the results obtained over a period of 10 years with contraception by monthly injection of 150 mg of dihydroxyprogesterone acetophenide, and 10 mg of estradiol enanthate. 100 fertile patients were observed, for a total of 8074 cycles. There were no pregnancies, and only minimal side effects. No changes were observed in blood profile, urine and hepatic function, and in blood coagulation; there were no instances of breast or uterine cancer. In 10 years only 15% of patients abandoned this method because of changes in the menstrual cycle, changes which were expected, but which had not been explained to the patients.^ieng