Clinical trial of intramuscular injection as contraceptive compound.
Med Gynaecol Sociol
; 5: 7-9, 1970.
Article
em En
| MEDLINE
| ID: mdl-12305458
ABSTRACT
PIP 99 women of proven fertility received 778 intramuscular contraceptive injections. An injectable compound containing 150 mg dihy droxyprogesterone acetophenide and 10 mg of estradiol enanthate (Deladroxate) in castor oil was prepared in a 1-cc disposable syringe. The injections were administered intramuscularly in the upper outer glut eal region on Day 8 of each menstrual cycle. The study was initiated in September 1965 and was completed by February 1969, with all data being recorded on a computer for future analysis. No pregnancies occurred. No serious side effects were noted. There were improvements in cases of dysmenorrhea and premenstrual tension. Minor complaints were not a problem in the use of the contraceptive except for intermenstrual spotting, which prompted 8 patients to discontinue the method. It is concluded that the long-acting intramuscular injection of estrogen-progesterone given once a month is effective and useful in difficult contraceptive patients in a public health clinic.^ieng
Palavras-chave
Algestone Acetophenide--administraction and dosage; Algestone Acetophenide--side effects; Biology; Clinical Research; Contraception; Contraceptive Agents, Estrogen--administraction and dosage; Contraceptive Agents, Estrogen--side effects; Contraceptive Agents, Female--administraction and dosage; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--administraction and dosage; Contraceptive Agents--side effects; Contraceptive Effectiveness; Dropouts; Estradiol Enanthate; Ethinyl Estradiol--administraction and dosage; Ethinyl Estradiol--side effects; Family Planning; Family Planning Programs; Injectables; Lactation; Maternal Physiology; Physiology; Research Methodology; Reversibility; Use-effectiveness
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Base de dados:
MEDLINE
Assunto principal:
Pacientes Desistentes do Tratamento
/
Pesquisa
/
Lactação
/
Acetofenida de Algestona
/
Etinilestradiol
/
Estudos de Avaliação como Assunto
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Evaluation_studies
Limite:
Pregnancy
Idioma:
En
Ano de publicação:
1970
Tipo de documento:
Article