New dimeric macrolide glycosides from the marine sponge Myriastra clavosa.
J Nat Prod
; 65(9): 1303-6, 2002 Sep.
Article
em En
| MEDLINE
| ID: mdl-12350152
ABSTRACT
Clavosolides A-D (1-4), dimeric macrolides incorporating cyclopropyl, tetrahydropyranyl, and glycosidic ring systems, were isolated from the cytotoxic extract of a Philippines collection of the marine sponge Myriastra clavosa. The structures of the clavosolides, which occurred as only trace metabolites, were elucidated through extensive NMR spectroscopic analyses. Clavosolides A (1) and B (2) were recently reported metabolites from M. clavosa, while the unsymmetrical dimers clavosolides C (3) and D (4) had new structures.
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Base de dados:
MEDLINE
Assunto principal:
Poríferos
/
Macrolídeos
/
Antineoplásicos
Limite:
Animals
/
Female
/
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article