The assessment of IgG avidity in the evaluation of perinatal herpes simplex virus infection.

Odièvre, Marie-Hélène; Cointe, Denis; Thébaud, Bernard; Zupan, Véronique; Ingrand, Didier; Lacaze-Masmonteil, Thierry; Grangeot-Keros, Liliane

Odièvre, Marie-Hélène; Cointe, Denis; Thébaud, Bernard; Zupan, Véronique; Ingrand, Didier; Lacaze-Masmonteil, Thierry; Grangeot-Keros, Liliane.

Afiliação

Odièvre MH; Service de Pédiatrie et Réanimation Néonatales, Hôpital Antoine-Béclère, Assistance Publique/Hôpitaux de Paris, Clamart, France.

J Perinatol ; 22(8): 669-71, 2002 Dec.

Article em En | MEDLINE | ID: mdl-12478453

RESUMO

Classical serologic assays are not useful for the diagnosis of perinatal herpes simplex virus (HSV) infection during the acute phase of the disease. We report two cases of neonatal HSV infection that highlight the diagnostic value of HSV-specific IgG avidity and its contribution for further characterization of neonatal HSV infection.

Assuntos

Afinidade de Anticorpos/fisiologia; Herpes Simples/sangue; Herpes Simples/fisiopatologia; Imunoglobulina G/sangue; Imunoglobulina G/fisiologia; Simplexvirus/fisiologia; Feminino; Humanos; Recém-Nascido; Masculino; Simplexvirus/isolamento & purificação

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Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Simplexvirus / Herpes Simples / Afinidade de Anticorpos Limite: Female / Humans / Male / Newborn Idioma: En Ano de publicação: 2002 Tipo de documento: Article

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