Iminosugars and relatives as antiviral and potential anti-infective agents.
Curr Top Med Chem
; 3(5): 513-23, 2003.
Article
em En
| MEDLINE
| ID: mdl-12570863
ABSTRACT
Iminosugars have emerged in the literature during mid-1960's as synthetic compounds. Around the same time, the first examples were found in Nature and their interesting enzyme inhibitory properties were recognised. Due to their powerful interference with glycohydrolases (glycosidases) as well as glycosyltransferases, quite a few representatives exhibit notable biological activities. These range from anti-diabetic, insect antifeedant, nematicidal, plant growth regulating to immunomodulating, anti-cancer as well as - in selected cases - anti-infective properties. The latter will be the focus of the following survey.
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Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Anti-Infecciosos
/
Monossacarídeos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article