[Impact of regulatory measures in the trends of community consumption of antibiotics in Chile]. / Impacto de medidas regulatorias en la tendencia de consumo comunitario de antibióticos en Chile.

ABSTRACT

BACKGROUND: The indiscriminate use of antibiotics increases the appearance of bacterial resistance and forces the use of more expensive alternatives. The Chilean Ministry of Health is regulating the consumption of antibiotics since September 1999. These regulatory measures restricted the sale of antibiotics only when these were prescribed by an MD or an DS. AIM: To study the impact of these regulatory measures on antibiotics sales in pharmacies. MATERIAL AND METHODS: A retrospective analysis of antibiotics sales in pharmacies from 1996 to 2000. The information was obtained from the International Marketing System (IMS Health), an auditing system of pharmacy sales. The consumption unit used was the Defined Daily Dose per 1000 inhabitants/day (DDD). RESULTS: There was an important reduction in DDD, after the introduction of regulatory measures, for amoxicillin, ampicillin, erythromycin, trimethoprim/sulpha, chroramphenicol, cloxacillin and phenoxymethylpenicillin. There was also a important fall in sales, expressed in dollars. CONCLUSIONS: The regulatory measures of the Ministry of Health, had an immediate and great impact on antibiotics sales in Chile.