Passive immunity in Helicobacter-challenged neonatal mice conferred by immunized dams lasts until weaning.
Infect Immun
; 71(4): 2226-9, 2003 Apr.
Article
em En
| MEDLINE
| ID: mdl-12654845
ABSTRACT
The objective of this study was to examine the effect of breast-feeding by immunized dams on Helicobacter colonization in newborns. Urease-based immunization regimens failed to protect nursing pups against H. felis, whereas H. felis lysate-cholera toxin resulted in protection. This observation correlated with a high recognition of cell surface-expressed bacterial antigens by milk antibodies. Protection lasted until weaning, indicating that infection is maintained at undetectable levels by passive immunity but then resumes when breast-feeding stops.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Desmame
/
Infecções por Helicobacter
/
Imunização
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Helicobacter
/
Imunidade Materno-Adquirida
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Anticorpos Antibacterianos
Limite:
Animals
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article