Quartz-crystal microbalance immunosensor for Schistsoma-japonicum-infected rabbit serum.
Anal Sci
; 19(3): 437-40, 2003 Mar.
Article
em En
| MEDLINE
| ID: mdl-12675355
ABSTRACT
A quartz-crystal microbalance immunosensor (QCM) has been developed for the direct determination of Schistosoma-japonicum-infected rabbit serum. A self-assembled monolayer with carboxyl groups was first coated on a gold electrode of a quartz-crystal resonator by the spontaneous adsorption of 3-mercaptopropionic acid. Schistosoma-japonicum molecular antigen of 32 kD molecular weight was then covalently attached to the crystal surface. The QCM immunosensor was used to detect infected rabbit serum (IRS49-2000); a maximum titer of 1800 was achieved.
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Base de dados:
MEDLINE
Assunto principal:
Quartzo
/
Schistosoma japonicum
/
Esquistossomose
/
Técnicas Biossensoriais
Limite:
Animals
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article