[Estrogen and bone metabolism in man].
Zhonghua Nan Ke Xue
; 9(1): 64-6, 2003 Feb.
Article
em Zh
| MEDLINE
| ID: mdl-12680338
ABSTRACT
In males, androgen can be aromatized into estrogen by aromatase. Estrogen receptors were shown to be present in male-derived human osteoblasts. For males bone is an important target tissue of estrogen. It was demonstrated that deficiency of estrogen or mutation of estrogen receptor gene in males could lead to osteopenia, even osteoporosis. Estrogens are required for the pubertal growth of bone and play important roles in maintenance of bone mass in males.
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Base de dados:
MEDLINE
Assunto principal:
Osso e Ossos
/
Receptores de Estrogênio
/
Estrogênios
/
Androgênios
Limite:
Animals
/
Humans
/
Male
Idioma:
Zh
Ano de publicação:
2003
Tipo de documento:
Article