[Vascular complications associated with inflammatory bowel disease]. / Complicaciones vasculares asociadas a la enfermedad inflamatoria intestinal.
An Med Interna
; 20(2): 81-4, 2003 Feb.
Article
em Es
| MEDLINE
| ID: mdl-12703161
ABSTRACT
Thromboembolic episode is a well known extraintestinal manifestation of inflammatory bowel disease, but it is a clinical rare complication. Histological and hematological studies suggest that a hypercoagulable state is involved in the pathogenesis of inflammatory bowel disease. However, the exact mechanism of hypercoagulability is still unknown. During the acute recurrences there is an increase of factor VIII, fibrinogen, platelet, factor V and decrease of antithrombin III. Hematologic disorders seem markedly correlated with the activity of the disease. We report on two patients with Inflammatory bowel disease and hypercoagulable state. We review the literature and discuss about the pathogenic mechanisms of such complication.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Arteriosclerose
/
Trombose
/
Colite Ulcerativa
/
Doença de Crohn
/
Isquemia Encefálica
/
Trombofilia
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
Es
Ano de publicação:
2003
Tipo de documento:
Article