Extracellular glutamate decrease in accumbens following cued food delivery.
Neuroreport
; 14(7): 991-4, 2003 May 23.
Article
em En
| MEDLINE
| ID: mdl-12802189
ABSTRACT
This study examined the effects of cued vs non-cued food delivery/consumption on extracellular glutamate and dopamine in the nucleus accumbens of food-deprived rats. Animals that always received a food pellet following a series of auditory tones showed a significant decrease in extracellular glutamate following food consumption, whereas animals that had not been previously exposed to tone-food pairing did not (p<0.05). In contrast, extracellular dopamine was significantly increased in the nucleus accumbens during the first time period after food consumption (p<0.05) regardless of whether animals had been exposed to prior tone-food pairing. Results suggest that food delivery/consumption is associated with a decrease in accumbal glutamate if food delivery has been previously paired with predictive environmental cues.
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Base de dados:
MEDLINE
Assunto principal:
Ácido Glutâmico
/
Sinais (Psicologia)
/
Ingestão de Alimentos
/
Espaço Extracelular
/
Privação de Alimentos
/
Núcleo Accumbens
Limite:
Animals
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article