Are follicular dendritic cells really good for nothing?
Nat Rev Immunol
; 3(9): 764-9, 2003 Sep.
Article
em En
| MEDLINE
| ID: mdl-12949500
Follicular dendritic cells (FDCs), which reside in the primary B-cell follicles and germinal centres of lymphoid tissues, can sequester antigen in the form of immune complexes and are thought to be pivotal to the germinal-centre reaction and the maintenance of immunological memory. But, many recent studies question the importance of FDCs and their bound immune complexes in B-cell responses. This article asks whether we can truly rule out a requirement for these cells in host defence.
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Base de dados:
MEDLINE
Assunto principal:
Células Dendríticas Foliculares
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article