Stabilities of hydroxyl radical spin adducts of PBN-type spin traps.
Free Radic Biol Med
; 12(2): 169-73, 1992.
Article
em En
| MEDLINE
| ID: mdl-1313775
ABSTRACT
The stability of the hydroxyl spin adduct of nine different PBN-type spin traps has been examined in phosphate buffer solutions of various pH. The hydroxyl adduct is produced by short illumination of hydrogen peroxide with UV light in the presence of spin trap and the decay of its EPR signal followed. The stability measured by the half life of the first-order decay is strongly dependent on the pH of the solution and the structure of the aromatic ring used in the trap. All hydroxyl adducts are more stable in acidic media. tert-Butyl hydroaminoxyl is detected as a degradation product of the hydroxyl adduct from all spin traps.
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Base de dados:
MEDLINE
Assunto principal:
Marcadores de Spin
/
Hidróxidos
/
Óxidos de Nitrogênio
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article