DNA flow cytometry of epithelioid sarcoma.

Pastel-Levy, C; Bell, D A; Rosenberg, A E; Preffer, F; Colvin, R B; Flotte, T J

Pastel-Levy, C; Bell, D A; Rosenberg, A E; Preffer, F; Colvin, R B; Flotte, T J.

Afiliação

Pastel-Levy C; Department of Pathology, Massachusetts General Hospital, Boston 02114.

Cancer ; 70(12): 2823-6, 1992 Dec 15.

Article em En | MEDLINE | ID: mdl-1451061

ABSTRACT

ABSTRACT

DNA ploidy of paraffin-embedded tissue from 11 patients with epithelioid sarcoma and 20 control specimens (granuloma annulare and sarcoid) was studied. DNA aneuploidy was found in 64% of the epithelioid sarcomas and in none of the control samples. Aneuploidy did not correlate with necrosis, vascular invasion, or mitotic rate. There was also no association of aneuploidy with adverse outcome.

Assuntos

DNA de Neoplasias/análise; Sarcoma/genética; Aneuploidia; DNA de Neoplasias/genética; Diploide; Citometria de Fluxo/métodos; Humanos; Inclusão em Parafina; Prognóstico; Estudos Retrospectivos; Sarcoma/patologia; Neoplasias de Tecidos Moles/genética; Neoplasias de Tecidos Moles/patologia

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Base de dados: MEDLINE Assunto principal: Sarcoma / DNA de Neoplasias Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 1992 Tipo de documento: Article

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