Role of macrophage inflammatory protein-1alpha in T-cell-mediated immunity to viral infection.
J Virol
; 77(22): 12378-84, 2003 Nov.
Article
em En
| MEDLINE
| ID: mdl-14581577
ABSTRACT
The immune response to lymphocytic choriomeningitis virus in mice lacking macrophage inflammatory protein-1alpha (MIP-1alpha) was evaluated. Generation of virus-specific effector T cells is unimpaired in MIP-1alpha-deficient mice. Furthermore, MIP-1alpha is not required for T-cell-mediated virus control or virus-induced T-cell-dependent inflammation. Thus, MIP-1alpha is not mandatory for T-cell-mediated antiviral immunity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Linfócitos T
/
Proteínas Inflamatórias de Macrófagos
/
Coriomeningite Linfocítica
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article