Relation of thrombomodulin gene polymorphisms to acute myocardial infarction in patients
Am J Cardiol
; 93(2): 204-7, 2004 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-14715348
ABSTRACT
Full-length sequencing of the thrombomodulin (TM) gene was obtained in 20 patients with premature acute myocardial infarction (AMI). Clinically relevant polymorphisms were identified and further evaluated in 145 patients with premature AMI and 143 controls. Despite the fact that TM promoter G-33A and C1418T polymorphisms are common in the Chinese population, the association between G-33A mutation and premature AMI indicates that we must focus on promoter G-33A polymorphism rather than C1418T polymorphism in terms of the role of TM gene mutation on premature AMI.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Regiões Promotoras Genéticas
/
Trombomodulina
/
Infarto do Miocárdio
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Regiões Promotoras Genéticas
/
Trombomodulina
/
Infarto do Miocárdio
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article