(+/-)-Schefflone: a trimeric monoterpenoid from the root bark of Uvaria scheffleri.
Phytochemistry
; 65(4): 399-404, 2004 Feb.
Article
em En
| MEDLINE
| ID: mdl-14759531
ABSTRACT
The trimeric monoterpene and mildly mosquito larvicidal agent, (+/-)-schefflone, that is an apparent derivative of the antiparasitic aromatic monoterpene espintanol, was isolated from the antimalarial extracts of the root bark of Uvaria scheffleri, together with espintanol. Structural determination of (+/-)-schefflone was achieved from spectroscopic data and confirmed by single-crystal X-ray diffraction analysis. (+/-)-Schefflone can be considered a product of a non-enzymatic Diels-Alder-type cycloaddition reaction of the quinonemethide derivative of espintanol as the diene and dienophile.
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Base de dados:
MEDLINE
Assunto principal:
Raízes de Plantas
/
Casca de Planta
/
Uvaria
/
Monoterpenos
Limite:
Animals
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article