Visualization of extrastriatal dopamine D2 receptors in the human brain.
Eur J Pharmacol
; 223(1): 105-7, 1992 Nov 13.
Article
em En
| MEDLINE
| ID: mdl-1478255
ABSTRACT
[123I]Epidepride, a potent and selective dopamine D2 radioligand, was administered to a 27 year old normal male volunteer. Single photon tomography revealed that peak striatal uptake occurred at 4 h after injection with a striatalcerebellar ratio of 7.8 rising to over 100 at 18 h post injection. Uptake above the levels seen in cerebellum was also noted in the thalamus, pituitary, hypothalamus and temporal lobe, particularly medially. Single photon tomography with [123I]epidepride allows visualization of extrastriatal dopamine D2 receptors in man.
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Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Receptores de Dopamina D2
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article