A dissociation of dorso-lateral striatum and amygdala function on the same stimulus-response habit task.
Neuroscience
; 124(3): 507-13, 2004.
Article
em En
| MEDLINE
| ID: mdl-14980722
This experiment tested the idea that the amygdala-based learning and memory system covertly acquires a stimulus-reward (stimulus-outcome) association during acquisition of a stimulus-response (S-R) habit task developed for the eight-arm radial maze. Groups of rats were given dorso-lateral striatal or amygdala lesions and then trained on the S-R habit task on the eight-arm radial maze. Rats with neurotoxic damage to the dorso-lateral striatum were severely impaired on the acquisition of the S-R habit task but showed a conditioned-cue preference for the stimulus reinforced during S-R habit training. Rats with neurotoxic damage to the amygdala were able to acquire the S-R habit task but did not show a conditioned-cue preference for the stimulus reinforced during S-R habit training. This pattern of results represents a dissociation of learning and memory functions of the dorsal striatum and amygdala on the same task.
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Base de dados:
MEDLINE
Assunto principal:
Neostriado
/
Condicionamento Clássico
/
Tonsila do Cerebelo
/
Aprendizagem
/
Memória
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Vias Neurais
Limite:
Animals
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article