Longitudinal syndromal and sub-syndromal symptoms after severe depression: 10-year follow-up study.
Br J Psychiatry
; 184: 330-6, 2004 Apr.
Article
em En
| MEDLINE
| ID: mdl-15056578
ABSTRACT
BACKGROUND:
Few follow-up studies of depression have evaluated depressive symptomatology over time at both threshold and sub-threshold levels.AIMS:
To evaluate long-term longitudinal symptomatic course after an episode of severe depression.METHOD:
A total of 61 participants from a previous study cohort underwent a detailed interview covering the longitudinal course of depression and pharmacological treatment over 8-11 years of follow-up.RESULTS:
Of the follow-up months, 52% were spent at an asymptomatic level, 15% at minor symptom level, 20% at residual symptom level and 13% at full depression level. Also, 30% of follow-up months were spent in an episode of depression, and 18% of patients never achieved asymptomatic status during follow-up. The percentage of patients at each symptom level remained relatively stable after the first 2 years, but levels in individuals fluctuated, with a mean of two changes in symptom levels per follow-up year.CONCLUSIONS:
After severe episodes, sub-syndromal levels of depression are common and persistent, with considerable fluctuation suggesting a continuum between sub-syndromal subtypes and full depression.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Transtorno Depressivo
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article