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Metabolic imaging of tissues by infrared fiber-optic spectroscopy: an efficient tool for medical diagnosis.
Hocdé, S; Loréal, O; Sire, O; Boussard-Plédel, C; Bureau, B; Turlin, B; Keirsse, J; Leroyer, P; Lucas, J.
Afiliação
  • Hocdé S; Universite de Rennes I, Laboratoire des Verres et Ceramiques, Avenue du General Leclerc, Campus de Beaulieu, 35042 Rennes Cedex, France.
J Biomed Opt ; 9(2): 404-7, 2004.
Article em En | MEDLINE | ID: mdl-15065908
Infrared fingerprints of molecules in biology contain much information on cells metabolism allowing one to distinguish between healthy and altered tissues. Here, to collect infrared signatures, we used evanescent wave spectroscopy based on an original infrared transmitting tapered glass fiber. A strict control of the fiber diameter in the tapered sensing zone allows high sensitivity and wide spectral range exploration from 800 to 3000 cm(-1). Then, merely in depositing the mouse liver biopsies on the fiber, this device has enable us to differentiate between tumorous and healthy tissues.
Assuntos
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Base de dados: MEDLINE Assunto principal: Análise Espectral / Tecnologia de Fibra Óptica / Raios Infravermelhos / Fígado Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2004 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Análise Espectral / Tecnologia de Fibra Óptica / Raios Infravermelhos / Fígado Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2004 Tipo de documento: Article