Transgene integration in plants: poking or patching holes in promiscuous genomes?
Curr Opin Biotechnol
; 15(2): 126-31, 2004 Apr.
Article
em En
| MEDLINE
| ID: mdl-15081050
ABSTRACT
Transgene integration in plants transformed by either Agrobacterium or direct DNA delivery methods occurs through illegitimate recombination (IR). The precise mechanism(s) for IR-mediated transgene integration and the role of host double-strand break repair enzymes remain unknown. A recent wealth of sequenced transgene loci and investigations aimed at genetically dissecting transgene integration mechanism(s) have provided new insights into the process.
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Base de dados:
MEDLINE
Assunto principal:
Plantas Geneticamente Modificadas
/
Transgenes
/
Reparo do DNA
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article