[Blood pressure goals in diabetes. A critical appraisal]. / Objetivos del tratamiento antihipertensivo en la población diabética. Una revisión crítica.
Med Clin (Barc)
; 122(15): 584-91, 2004 Apr 24.
Article
em Es
| MEDLINE
| ID: mdl-15144748
ABSTRACT
In this article we review the evidence supporting the need to achieve a target blood pressure (BP) under 130-80 mm Hg in diabetic patients, as recent international guidelines recommend (JNC VII, ESH-ESC and ADA). We have analyzed the explicit arguments used in these guidelines, 3 clinical trials designed to determine which is the best BP in diabetics (HOT, UKPDS-38 and ABCD) as well as other potentially misleading clinical trials. In our opinion, neither these 3 specific clinical trials nor other trials quoted in the guidelines (due to results and methodology employed) can answer the question of the best goal of pharmacological treatment for hypertension in diabetics. On the other hand, international agreements are not sufficiently rigorous regarding both the sources mentioned and the direct interpretation of the data provided. We conclude that there is not enough evidence to support the goal pressure below 130/80 mm Hg in patients with diabetes. We insist in the need of individualization of therapy in patients and consider that a under 140/85 mm Hg goal pressure in diabetics is perfectly supported by current evidence.
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Base de dados:
MEDLINE
Assunto principal:
Pressão Sanguínea
/
Diabetes Mellitus
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
Es
Ano de publicação:
2004
Tipo de documento:
Article