Crystal structure of an empty capsid of turnip yellow mosaic virus.
J Mol Biol
; 341(5): 1205-14, 2004 Aug 27.
Article
em En
| MEDLINE
| ID: mdl-15321716
ABSTRACT
Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas Virais
/
Capsídeo
/
Tymovirus
/
Estrutura Quaternária de Proteína
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article