Multiple myeloma complicated by autoimmune hemolytic anemia.
Intern Med
; 43(7): 595-8, 2004 Jul.
Article
em En
| MEDLINE
| ID: mdl-15335188
ABSTRACT
A 57-year-old man was admitted with severe anemia and hypergamma globulinemia. After a diagnosis of multiple myeloma and autoimmune hemolytic anemia was made, chemotherapy rapidly decreased the M-protein level and improved his anemia with normalization of the direct Coombs test. The immunoglobulin binding to the patient's red cells was immunoglobulin G kappa chain like the myeloma M-protein. However, monoclonal immunoglobulin G derived from short-term culture of the patient's bone marrow mononuclear cells did not bind to a panel of red cells. Therefore, the relationship between the M protein produced by his myeloma cells and hemolysis remained unclear.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Proteínas do Mieloma
/
Anemia Hemolítica Autoimune
/
Mieloma Múltiplo
Tipo de estudo:
Etiology_studies
Limite:
Humans
/
Male
/
Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article