[Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome]. / Elévation majeure de l'uricémie associée à des vomissements au cours du troisième trimestre de la grossesse: cinq cas avec issue favorable.

ABSTRACT

We report five cases of vomiting associated with a very important increase of maternal plasma uric acid (> 595 mmol/l, 100 mg/l) at the third trimester of pregnancy. In all cases, elevation was transitory and regressive with rehydratation. Pregnancies proceeded normally to term and delivered healthy babies. An important rise of plasmatic uric acid during pregnancy can be found in severe hypertensive disorders (preeclampsia, HELLP syndrome, acute fatty liver). Nevertheless, it can be related to transient renal insufficiency without any severe pathology. In our five observations, digestive disorders seem to be the reason for this phenomenon and spontaneous prognosis was excellent in all cases.