[Chromosomic etiology of male sterility and infertility]. / Etiología cromosómica de la esterilidad e infertilidad masculina.
Ginecol Obstet Mex
; 60: 14-21, 1992 Jan.
Article
em Es
| MEDLINE
| ID: mdl-1555787
ABSTRACT
Recent advances in the knowledge of sexual development have been obtained by studying individuals with dysgenetic gonads and reproductive tract alterations. By using probes Y-ADN in these patients, it was found that a gene of the short arms of Y chromosome, induces testicular differentiation. The way this gene acts is not known, but the observation that there are homologue sequencies in X and Y, suggests the possibility that sexual differentiation depends on genic doses. Other genes like the one that codifies for antigen H-Y, for skeletal maturation, body growth, dental size and spermatogenesis regulation, have been identified in chromosome Y. Findings that have allowed a better understanding of genetic and cytogenetic factor involved in sterility-infertility.
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Base de dados:
MEDLINE
Assunto principal:
Aberrações dos Cromossomos Sexuais
/
Cromossomo Y
/
Infertilidade Masculina
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Humans
/
Male
Idioma:
Es
Ano de publicação:
1992
Tipo de documento:
Article