A subinhibitory concentration of clarithromycin inhibits Mycobacterium avium biofilm formation.

Carter, George; Young, Lowell S; Bermudez, Luiz E

Carter, George; Young, Lowell S; Bermudez, Luiz E.

Afiliação

Carter G; Kuzell Institute, California Pacific Medical Center Research Institute, San Francisco, California, USA.

Antimicrob Agents Chemother ; 48(12): 4907-10, 2004 Dec.

Article em En | MEDLINE | ID: mdl-15561879

ABSTRACT

ABSTRACT

Mycobacterium avium causes disseminated infection in immunosuppressed individuals and lung infection in patients with chronic lung diseases. M. avium forms biofilm in the environment and possibly in human airways. Antibiotics with activity against the bacterium could inhibit biofilm formation. Clarithromycin inhibits biofilm formation but has no activity against established biofilm.

Assuntos

Antibacterianos/farmacologia; Biofilmes/efeitos dos fármacos; Claritromicina/farmacologia; Complexo Mycobacterium avium/efeitos dos fármacos; Síndrome da Imunodeficiência Adquirida/sangue; Compostos Aza/farmacologia; Azitromicina/farmacologia; Fluoroquinolonas; Humanos; Testes de Sensibilidade Microbiana; Microscopia Eletrônica de Varredura; Moxifloxacina; Infecção por Mycobacterium avium-intracellulare/microbiologia; Quinolinas/farmacologia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complexo Mycobacterium avium / Claritromicina / Biofilmes / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2004 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google