Complete cDNA sequence of bovine alpha 1-antitrypsin.
Biochim Biophys Acta
; 1130(2): 209-12, 1992 Mar 24.
Article
em En
| MEDLINE
| ID: mdl-1562597
ABSTRACT
A cDNA clone coding for the entire bovine alpha 1-antitrypsin molecule has been isolated from a lambda gt11 bovine liver cDNA library using a human alpha 1-antitrypsin cDNA as a probe. The bovine cDNA was sequenced by the dideoxynucleotide chain termination method. Comparison of the translated amino acid sequence of the bovine alpha 1-antitrypsin with those of the human, baboon, sheep, rat and mouse demonstrates the preservation of most of the critical structural determinants. The bovine and the sheep molecules have a sequence homology of 94% and both the molecules contain four cysteine residues; there is only one cysteine in the others.
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Base de dados:
MEDLINE
Assunto principal:
DNA
/
Alfa 1-Antitripsina
Limite:
Animals
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article