Microwave-assisted synthesis of novel thiazolocarbazoles and evaluation as potential anticancer agents. Part III.
J Enzyme Inhib Med Chem
; 19(6): 467-73, 2004 Dec.
Article
em En
| MEDLINE
| ID: mdl-15662950
ABSTRACT
Novel 6-substituted thiazolocarbazole derivatives have been synthesized under microwave irradiation via the corresponding imino-1,2,3-dithiazoles. In vitro antitumor potential of these polyheterocyclic compounds was evaluated. Among all the tested thiazolocarbazoles, compound 10 is the most effective in inhibiting cell growth.
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Base de dados:
MEDLINE
Assunto principal:
Tiazóis
/
Carbazóis
/
Micro-Ondas
/
Antineoplásicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article