Your browser doesn't support javascript.
loading
Validity of Simpson-Angus Scale (SAS) in a naturalistic schizophrenia population.
Janno, Sven; Holi, Matti M; Tuisku, Katinka; Wahlbeck, Kristian.
Afiliação
  • Janno S; Department of Psychiatry, University of Tartu, Raja 31, 50417, Tartu, Estonia. svenjanno@hot.ee
BMC Neurol ; 5(1): 5, 2005 Mar 17.
Article em En | MEDLINE | ID: mdl-15774006
ABSTRACT

BACKGROUND:

Simpson-Angus Scale (SAS) is an established instrument for neuroleptic-induced parkinsonism (NIP), but its statistical properties have been studied insufficiently. Some shortcomings concerning its content have been suggested as well. According to a recent report, the widely used SAS mean score cut-off value 0.3 of for NIP detection may be too low. Our aim was to evaluate SAS against DSM-IV diagnostic criteria for NIP and objective motor assessment (actometry).

METHODS:

Ninety-nine chronic institutionalised schizophrenia patients were evaluated during the same interview by standardised actometric recording and SAS. The diagnosis of NIP was based on DSM-IV criteria. Internal consistency measured by Cronbach's alpha, convergence to actometry and the capacity for NIP case detection were assessed.

RESULTS:

Cronbach's alpha for the scale was 0.79. SAS discriminated between DSM-IV NIP and non-NIP patients. The actometric findings did not correlate with SAS. ROC-analysis yielded a good case detection power for SAS mean score. The optimal threshold value of SAS mean score was between 0.65 and 0.95, i.e. clearly higher than previously suggested threshold value.

CONCLUSION:

We conclude that SAS seems a reliable and valid instrument. The previously commonly used cut-off mean score of 0.3 has been too low resulting in low specificity, and we suggest a new cut-off value of 0.65, whereby specificity could be doubled without loosing sensitivity.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Transtornos Parkinsonianos / Testes Neuropsicológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2005 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Transtornos Parkinsonianos / Testes Neuropsicológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2005 Tipo de documento: Article