[Prediction of serotypes of dengue virus by response to IgM antibodies]. / Predicción del serotipo del virus del dengue mediante la respuesta de anticuerpos IgM.
Rev Cubana Med Trop
; 54(2): 113-7, 2002.
Article
em Es
| MEDLINE
| ID: mdl-15849937
ABSTRACT
A study of 4 groups of serum samples from Cuba, Costa Rica, Nicaragua and Panama was made to determine the serotypes of dengue virus causing epidemics or outbreaks by using IgM antibody-capture ELISA(MAC-ELISA). Dengue-IgM diagnostic kit was independently used in each of the serotypes and an index value was calculated (optical density of the sample/cut-off value) in each case, with which two statistical analyses were made Fisher's variances and Litter significant difference (LSD) calculation. Such calculations allowed determining that in Cuba and Panama, serotype 2 circulated whereas in Costa Rica, serotype 1 prevailed. These were the isolated serotypes in various epidemics. Regarding Nicaragua, very heterogeneous responses were obtained, the responsible serotype could not be determined since more than two serotypes co-circulated in this country.
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Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina M
/
Vírus da Dengue
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
Es
Ano de publicação:
2002
Tipo de documento:
Article