Anti-HIV protease activity from rosa family plant extracts and rosamultin from Rosa rugosa.
J Med Food
; 8(1): 107-9, 2005.
Article
em En
| MEDLINE
| ID: mdl-15857219
ABSTRACT
To identify substances with anti-human immunodeficiency virus (HIV) activity from plant sources, 12 extracts of Rosa family plants were screened for their inhibitory effects against HIV-1 protease. Of the extracts tested, the strongest inhibitory effects were observed in the root of Rosa rugosa and the leaves of Prunus sargentii, at a concentration of 100 microg/mL. Rosamultin isolated from the root of R. rugosa inhibited HIV-1 protease by 53% at a concentration of 100 microM.
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Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Extratos Vegetais
/
Infecções por HIV
/
HIV-1
/
Inibidores da Protease de HIV
/
Rosa
/
Fitoterapia
Limite:
Humans
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article