Antiviral evaluation of plants from Brazilian Atlantic Tropical Forest.

Andrighetti-Fröhner, C R; Sincero, T C M; da Silva, A C; Savi, L A; Gaido, C M; Bettega, J M R; Mancini, M; de Almeida, M T R; Barbosa, R A; Farias, M R; Barardi, C R M; Simões, C M O

Andrighetti-Fröhner, C R; Sincero, T C M; da Silva, A C; Savi, L A; Gaido, C M; Bettega, J M R; Mancini, M; de Almeida, M T R; Barbosa, R A; Farias, M R; Barardi, C R M; Simões, C M O.

Afiliação

Andrighetti-Fröhner CR; Laboratório de Virologia Aplicada, Universidade Federal de Santa Catarina, Campus Universitário Trindade, Florianópolis, SC, Brazil.

Fitoterapia ; 76(3-4): 374-8, 2005 Jun.

Article em En | MEDLINE | ID: mdl-15890472

ABSTRACT

ABSTRACT

The antiviral activity of six medicinal plants from Brazilian Atlantic Tropical Forest was investigated against two viruses herpes simplex virus type 1 (HSV-1) and poliovirus type 2 (PV-2). Cuphea carthagenensis and Tillandsia usneoides extracts showed the best antiherpes activity. T. usneoides dichloromethane, ethyl acetate and n-butanol extracts, and Lippia alba n-butanol extract showed inhibition of HSV-1, strain 29R/acyclovir resistant. In addition, only L. alba ethyl acetate extract showed antipoliovirus activity. These results corroborate that medicinal plants can be a rich source of potential antiviral compounds.

Assuntos

Antivirais/farmacologia; Herpesvirus Humano 1/efeitos dos fármacos; Magnoliopsida/química; Extratos Vegetais/farmacologia; Poliovirus/efeitos dos fármacos; Antivirais/química; Brasil; Farmacorresistência Viral; Extratos Vegetais/química

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Base de dados: MEDLINE Assunto principal: Antivirais / Extratos Vegetais / Herpesvirus Humano 1 / Magnoliopsida / Poliovirus País como assunto: America do sul / Brasil Idioma: En Ano de publicação: 2005 Tipo de documento: Article

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