Serologic evidence of exposure of wild mammals to flaviviruses in the central and eastern United States.
Am J Trop Med Hyg
; 72(5): 622-30, 2005 May.
Article
em En
| MEDLINE
| ID: mdl-15891139
ABSTRACT
Serosurveys were conducted to obtain flavivirus and West Nile virus (WNV) seroprevalence data from mammals. Sera from 513 small- and medium-sized mammals collected during late summer and fall 2003 from Colorado, Louisiana, New York, Ohio, and Pennsylvania were screened for flavivirus-specific antibodies. Sera samples containing antibody to flaviviruses were screened for WNV-specific antibodies by epitope-blocking enzyme-linked immunosorbent assays and confirmed with plaque reduction neutralization tests. Prevalence of WNV antibodies among study sites ranged from 0% to 42.8% among the mammal communities sampled. High prevalence rates for WNV were noted among raccoons (100%, with a very small sample size, N = 2), Virginia opossums (50.0%), fox squirrels (49.1%), and eastern gray squirrels (48.3%). The high WNV antibody prevalence noted for tree squirrels, the peri-domestic tendencies of several of these species, and their ease of observation could make these species useful sentinels for monitoring WNV activity within urban communities.
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Base de dados:
MEDLINE
Assunto principal:
Roedores
/
Didelphis
/
Flavivirus
/
Animais Selvagens
/
Anticorpos Antivirais
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article