Serum copper, ceruloplasmin and thiobarbituric acid reactive substance status in patients with ovarian cancer.
Indian J Physiol Pharmacol
; 48(4): 486-8, 2004 Oct.
Article
em En
| MEDLINE
| ID: mdl-15907060
ABSTRACT
Serum copper, ceruloplasmin and thiobarbituric acid reactive substances (TBARS) were estimated in 30 patients of ovarian cancer. The copper to ceruloplasmin ratio was moderately increased (P<0.05) but the copper (P<0.01( and ceruloplasmin (P<0.001) levels were significantly increased in ovarian cancer patients as compared to controls. TBARS levels were also found to be highly significant (P<0.001). Trace elements and free radicals have been implicated in the etiology of cancer. Hence the estimation of antioxidants like ceruloplasmin and TBARS along with the trace element like copper may be of value in the early diagnosis of cancer.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Ceruloplasmina
/
Substâncias Reativas com Ácido Tiobarbitúrico
/
Cobre
Tipo de estudo:
Screening_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article