Toxic hepatitis associated with paroxetine.
Int J Clin Pract
; 59(7): 861-2, 2005 Jul.
Article
em En
| MEDLINE
| ID: mdl-15963219
ABSTRACT
Hepatotoxicity is a rare complication of paroxetine, a selective serotonin reuptake inhibitor. Regarded as safe in therapeutic use, there have been reports of cases of severe hepatic dysfunction with gross elevations of transaminase levels that may be related to this drug. We report here severe adverse cholestatic and hepatocellular injury in a patient taking paroxetine probably due to an immune-mediated hypersensitivity reaction.
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Base de dados:
MEDLINE
Assunto principal:
Paroxetina
/
Doença Hepática Induzida por Substâncias e Drogas
/
Antidepressivos
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article