Splenic marginal zone lymphoma: 7q abnormalities.
Methods Mol Med
; 115: 241-50, 2005.
Article
em En
| MEDLINE
| ID: mdl-15998972
ABSTRACT
7q abnormalities are the most common cytogenetic or genetic aberrations found in splenic marginal zone lymphoma. The molecular methods whereby these regions of genetic loss can be characterized are discussed in this chapter. Emphasis is given to careful experimental design, for example sample purification and optimization, that is, ensuring that only target sequences are amplified. There also is discussion of result interpretation, pitfalls that may be encountered, and alternative visualization techniques that might be used.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Esplênicas
/
Cromossomos Humanos Par 7
/
DNA de Neoplasias
/
Linfoma de Células B
/
Separação Imunomagnética
/
Perda de Heterozigosidade
/
Citometria de Fluxo
Limite:
Humans
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article