Predictors of schizophrenia: evidence from the Northern Finland 1966 Birth Cohort and other sources.
Br J Psychiatry Suppl
; 48: s4-7, 2005 Aug.
Article
em En
| MEDLINE
| ID: mdl-16055806
ABSTRACT
BACKGROUND:
Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis.AIMS:
To outline the development of schizophrenia.METHOD:
We drew on evidence from The Northern Finland 1966 Birth Cohort supplemented by selected findings from other relevant literature.RESULTS:
The main known risk factors in development of schizophrenia are genetic causes, pregnancy and delivery complications, slow neuromotor development, and deviant cognitive and academic performance. However, their effect size and predictive power are small.CONCLUSIONS:
No powerful risk factor, premorbid sign or risk indicator has been identified that is useful for the prediction of schizophrenia in the general population.
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Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Deficiências do Desenvolvimento
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Child
/
Female
/
Humans
/
Male
/
Pregnancy
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article