Geographical distribution of genetic polymorphism of the pathogen Histoplasma capsulatum isolated from infected bats, captured in a central zone of Mexico.
FEMS Immunol Med Microbiol
; 45(3): 451-8, 2005 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-16061361
ABSTRACT
Fourteen Histoplasma capsulatum isolates recovered from infected bats captured in Mexican caves and two human H. capsulatum reference strains were analyzed using random amplification of polymorphic DNA PCR-based and partial DNA sequences of four genes. Cluster analysis of random amplification of polymorphic DNA-patterns revealed differences for two H. capsulatum isolates of one migratory bat Tadarida brasiliensis. Three groups were identified by distance and maximum-parsimony analyses of arf, H-anti, ole, and tub1 H. capsulatum genes. Group I included most isolates from infected bats and one clinical strain from central Mexico; group II included the two isolates from T. brasiliensis; the human G-217B reference strain from USA formed an independent group III. Isolates from group II showed diversity in relation to groups I and III, suggesting a different H. capsulatum population.
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Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Quirópteros
/
Histoplasma
/
Histoplasmose
Limite:
Animals
/
Humans
/
Male
País como assunto:
Mexico
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article