Upper vaginectomy for the treatment of vaginal intraepithelial neoplasia.
Am J Obstet Gynecol
; 193(2): 577-80; discussion 580-1, 2005 Aug.
Article
em En
| MEDLINE
| ID: mdl-16098901
ABSTRACT
OBJECTIVE:
The purpose of this study was to evaluate the use of upper vaginectomy for the treatment of vaginal intraepithelial neoplasia (VAIN). STUDYDESIGN:
We conducted a retrospective review. Between August 1, 1985 and April 30, 2004, 105 patients were identified who had undergone upper vaginectomy for VAIN.RESULTS:
Thirty-six patients had previously been treated for VAIN. Mean operative time and estimated blood loss were 55 minutes and 113 mL, respectively. Ten percent had intraoperative complications. Twenty-three (22%) patients had negative findings on final pathologic examination, and invasive cancer was found in 13 (12%) patients. Four patients had postoperative complications. Follow-up was available in 52 patients; 46 (88%) remain without recurrence at a mean follow-up of 25 months.CONCLUSION:
In our patients, upper vaginectomy was efficacious for the treatment of VAIN. The procedure led to the diagnosis of occult invasive cancer in 12% of these women.
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Base de dados:
MEDLINE
Assunto principal:
Vagina
/
Neoplasias Vaginais
/
Carcinoma in Situ
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article