Severe hypothyroidism due to atrophic thyroiditis from second year of life influenced developmental outcome.
Acta Paediatr
; 94(8): 1049-54, 2005 Aug.
Article
em En
| MEDLINE
| ID: mdl-16188848
ABSTRACT
UNLABELLED From the second year of life a girl showed an insidious development of clinical hypothyroidism due to a non-goitrous lymphocytic thyroiditis without traceable circulating levels of thyroid antibodies measured by routine immunoassays. The diagnostic delay of this rare variant of atrophic thyroiditis caused persistent neuropsychological deficits. CONCLUSION:
Her difficulties with speed of processing and working memory in particular could suggest a frontal deficit, possibly in the dorsolateral prefrontal circuit. This contrasts with findings in congenital hypothyroidism, suggesting a relatively preserved frontal function, and could illustrate different neuropsychological deficits of hypothyroidism at different ages in early childhood.
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Base de dados:
MEDLINE
Assunto principal:
Tiroxina
/
Tireoidite Autoimune
/
Deficiências do Desenvolvimento
/
Transtornos do Crescimento
/
Hipotireoidismo
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article