Clinical and dermoscopic changes in common melanocytic nevi in school children: the Framingham school nevus study.
Dermatology
; 211(3): 234-9, 2005.
Article
em En
| MEDLINE
| ID: mdl-16205068
ABSTRACT
BACKGROUND:
Nevi are potential precursors of malignant melanoma and are important risk factors for the development of the disease. Childhood may be a critical time for the formation and evolution of nevi.OBJECTIVES:
To document the development of new nevi and to document the clinical and dermoscopic changes in index nevi in school children during a 1-year follow-up.METHODS:
Digital photographs and dermoscopic images of the back of subjects were compared at baseline and 1-year follow-up to assess changes in nevi counts and in clinical and dermoscopic features of index nevi.RESULTS:
Overall participation rate was 81% (42/52). 56.4% of study participants were found to have an increased number of nevi at 1-year follow-up. All nevi were small and clinically insignificant. Fifty percent of study participants were found to have dermoscopic changes in their index nevi at 1-year follow-up. Eighty-five percent of these changes were classified as subtle and 15.0% as obvious.CONCLUSIONS:
A significant portion of students developed new nevi over the course of 1 year. Most index nevi remained stable in pattern and structure. Benign dermoscopic changes occurred in 50.0% of index nevi. However, none of the dermoscopically changed nevi revealed any major changes and the overall nevus pattern remained unchanged. The relevance of these changes is uncertain and further follow-up may elucidate their significance.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Nevo Pigmentado
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Humans
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article