Proteomics of organelles and large cellular structures.
Nat Rev Mol Cell Biol
; 6(9): 702-14, 2005 Sep.
Article
em En
| MEDLINE
| ID: mdl-16231421
ABSTRACT
The mass-spectrometry-based identification of proteins has created opportunities for the study of organelles, transport intermediates and large subcellular structures. Traditional cell-biology techniques are used to enrich these structures for proteomics analyses, and such analyses provide insights into the biology and functions of these structures. Here, we review the state-of-the-art proteomics techniques for the analysis of subcellular structures and discuss the biological insights that have been derived from such studies.
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Base de dados:
MEDLINE
Assunto principal:
Organelas
/
Proteoma
/
Proteômica
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article