Your browser doesn't support javascript.
loading
3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium.
Rüegg, T; Calderón, A I; Queiroz, E F; Solís, P N; Marston, A; Rivas, F; Ortega-Barría, E; Hostettmann, K; Gupta, M P.
Afiliação
  • Rüegg T; Center for Pharmacognostic Research on Panamanian Flora (CIFLORPAN), College of Pharmacy, University of Panama, Apartado 10767, Panama, Panama.
J Ethnopharmacol ; 103(3): 461-7, 2006 Feb 20.
Article em En | MEDLINE | ID: mdl-16266794
A new prenylated salicylic acid derivative, 3-farnesyl-2-hydroxy benzoic acid (1), was isolated from the leaves of Piper multiplinervium C. DC. (Piperaceae). It showed anti-Helicobacter pylori activity (MIC 37.5 microg/ml) and antimicrobial activity at MICs between 2.5 and 5 microg/ml against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Mycobacterium smegmatis, Pseudomonas aeruginosa and Candida albicans. Its structure was elucidated by means of MS, 1H and 13C NMR. The ethnomedical claim of Piper multiplinervium to treat stomach aches by the Kuna Indians of Panama may be justified by anti-Helicobacter pylori activity of its MeOH extract.
Assuntos
Buscar no Google
Base de dados: MEDLINE Assunto principal: Helicobacter pylori / Piper / Farneseno Álcool / Hidroxibenzoatos / Anti-Infecciosos País como assunto: America central / Panama Idioma: En Ano de publicação: 2006 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Helicobacter pylori / Piper / Farneseno Álcool / Hidroxibenzoatos / Anti-Infecciosos País como assunto: America central / Panama Idioma: En Ano de publicação: 2006 Tipo de documento: Article