OSEM reconstruction, associated with temporal fourier and depth-dependant resolution recovery filtering, enhances results from sestamibi and 201Tl 16-interval gated SPECT.
J Nucl Med
; 46(11): 1789-95, 2005 Nov.
Article
em En
| MEDLINE
| ID: mdl-16269591
ABSTRACT
UNLABELLED Gated SPECT recorded with 16 intervals determines left ventricular (LV) ejection fraction more accurately than does gated SPECT recorded with 8 intervals but produces higher image noise. This study aimed to assess the results from sestamibi and (201)Tl 16-interval gated SPECT when both signal-to-noise ratio and spatial resolution were enhanced with an original method of reconstruction. METHODS:
Forty patients with coronary artery disease underwent (201)Tl and sestamibi 16-interval gated SPECT and, to be used as a reference, cardiac MRI. Assessments of global and regional LV function provided by ordered-subsets expectation maximization (OSEM) with depth-dependant resolution recovery and temporal Fourier filtering were compared with those from conventional filtered backprojection (FBP) previously optimized by screening various filter frequencies and various temporal smoothing levels.RESULTS:
For both tracers, LV ejection fraction was determined best when the association of OSEM with depth-dependant resolution recovery was used alone, with temporal Fourier filtering, or with a slight 2-frame temporal smoothing Mean absolute values of relative errors ranged from 3.2% to 3.6% (4.0%-7.9% for FBP), and coefficient correlation ranged from 0.91 to 0.93 (0.70-0.91 for FBP). Among these 3 reconstruction methods, the association of OSEM with depth-dependant resolution recovery with temporal Fourier filtering provided the highest signal-to-noise ratio, with mean increases of 54% for sestamibi and 80% for (201)Tl when compared with FBP, and the best analysis of segmental contractility, with exact agreement rates with MRI being 73% for (201)Tl and 79% for sestamibi.CONCLUSION:
OSEM associated with temporal Fourier filtering and depth-dependant resolution recovery filtering enhances the LV function assessment provided by sestamibi and (201)Tl 16-interval gated SPECT and dramatically reduces image noise, a property that enhances and facilitates image interpretation.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Volume Sistólico
/
Tálio
/
Doença da Artéria Coronariana
/
Aumento da Imagem
/
Imagem do Acúmulo Cardíaco de Comporta
/
Tecnécio Tc 99m Sestamibi
/
Disfunção Ventricular Esquerda
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article