Five labdane diterpenoids from the seeds of Aframomum zambesiacum.
Phytochemistry
; 67(5): 433-8, 2006 Mar.
Article
em En
| MEDLINE
| ID: mdl-16321410
ABSTRACT
Five labdane diterpenoids, (3-5), zambesiacolactone A (7) and zambesiacolactone B (8), were isolated from the seeds of Aframomum zambesiacum (Baker) K. Schum., along with five known labdanes and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Their antiplasmodial activity was evaluated in vitro against Plasmodium falciparum. Compound 3 was the most active with an IC(50) value of 4.97 microM.
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Base de dados:
MEDLINE
Assunto principal:
Sementes
/
Zingiberaceae
/
Diterpenos
Limite:
Animals
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article