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Comparison of Tc-99m sestamibi and F-18 FDG-PET in the assessment of multiple myeloma.
Hung, Guang-Uei; Tsai, Chien-Chung; Tsai, Shih-Chuan; Lin, Wan-Yu.
Afiliação
  • Hung GU; Department of Nuclear Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Anticancer Res ; 25(6C): 4737-41, 2005.
Article em En | MEDLINE | ID: mdl-16334169
BACKGROUND: Tc-99m methoxy-isobutyl-isonitrile (MIBI) has been reported to be a useful tracer in patients with multiple myeloma (MM). Few articles have reported the potential value of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) in the evaluation of MM. Therefore, the purpose of this study was to compare the diagnostic abilities of the MIBI scan and the FDG-PET scan in the evaluation of MM. MATERIALS AND METHODS: Twelve patients with MM were included. All patients received a radiological skeletal survey, MIBI scan and FDG-PET scan. RESULTS: Thirty-four lesions (19 soft tissue lesions and 15 skeletal lesions) plus 5 cases of bone marrow involvement were detected. The conventional skeletal X-ray survey detected 4 soft tissue lesions (21.1%), 12 skeletal lesions (80%), but no bone marrow involvement (0%). The MIBI scan found 4 cases of bone marrow involvement (80%), 13 soft tissue lesions (68.4%) and 12 skeletal lesions (80%). The PET scan detected 5 cases of bone marrow involvement (100%), 17 soft tissue lesions (89.5%) and 14 skeletal lesions (93.3%). CONCLUSION: Both the MIBI and the FDG-PET scans are useful in the evaluation of patients with MM. However, FDG-PET can detect more lesions than the MIBI scan in patients with MM.
Assuntos
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Base de dados: MEDLINE Assunto principal: Tecnécio Tc 99m Sestamibi / Compostos Radiofarmacêuticos / Fluordesoxiglucose F18 / Mieloma Múltiplo Tipo de estudo: Evaluation_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2005 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Tecnécio Tc 99m Sestamibi / Compostos Radiofarmacêuticos / Fluordesoxiglucose F18 / Mieloma Múltiplo Tipo de estudo: Evaluation_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2005 Tipo de documento: Article