[Potentiation of the acute toxic effects of cocaine by ethyl alcohol]. / Potentialisation des effets toxiques aigus de la cocaïne par l'alcool éthylique.
Bull Acad Natl Med
; 176(2): 193-7, 1992 Feb.
Article
em Fr
| MEDLINE
| ID: mdl-1633559
ABSTRACT
Ethyl alcohol increases significantly the lethality of cocaine intoxication in the rat. This lethality is not modified by nicardipine or flunarizine, antidotes to cocaine, and might be due to the formation of a newly identified active metabolite cocaethylene. In addition alcohol like cocaine inhibits the baro receptor reflex.
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Base de dados:
MEDLINE
Assunto principal:
Cocaína
/
Etanol
Limite:
Animals
Idioma:
Fr
Ano de publicação:
1992
Tipo de documento:
Article