A patient with monosomy 7 and polyuria.
Leuk Res
; 16(6-7): 711-5, 1992.
Article
em En
| MEDLINE
| ID: mdl-1635385
ABSTRACT
Diabetes insipidus (DI) is a rare complication of leukaemia. An association between monosomy 7 and DI in leukaemias has been proposed. We present a case of Ph1-positive CML who developed polyuria at the time of lymphoid blast transformation associated with loss of chromosome 7. Biochemical results were not diagnostic of DI and a therapeutic trial of DDAVP was unsuccessful. Post-mortem showed a peripituitary and renal leukaemic infiltrate and although DI is a possibility, the cause of his polyuria remains unresolved.
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Base de dados:
MEDLINE
Assunto principal:
Poliúria
/
Cromossomos Humanos Par 7
/
Monossomia
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article